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Peyton Manning is one of many Colts who can’t currently contribute

Philadelphia Eagles v Detroit Lions

DETROIT, MI - SEPTEMBER 19: Linebacker Ernie Sims #50 of the Philadelphia Eagles observes the National Anthem during the game against the Detroit Lions on September 19, 2010 at Ford Field in Detroit, Michigan. (Photo by Drew Hallowell/Philadelphia Eagles/Getty Images)

Drew Hallowell

The biggest news out of Colts camp is and has been the ongoing unavailability of quarterback Peyton Manning, who is recovering from his second neck surgery in as many years.

But plenty of other players are currently missing.

Absent from a Wednesday night practice were 10 players, including veteran linebacker Ernie Sims (pictured) and defensive end Jamaal Anderson. Sims recently underwent an appendectomy, and Anderson has a groin injury.

On Saturday night, the Colts face the Rams in St. Louis to open the preseason.