Cardinals guard Jonathan Cooper has broken leg

AP

The Cardinals have lost their first-round pick indefinitely.

Rookie left guard Jonathan Cooper suffered a broken leg in the third quarter of Saturday night’s exhibition loss to San Diego, coach Bruce Arians said, according to multiple reports. Per multiple media outlets, Cooper has a broken fibula.

Cooper was injured when he was blocking downfield on a running play. As running back Alfonso Smith was being tackled, the collision took out Cooper, who was not facing the play.

If the Cardinals believe there’s a chance Cooper could heal in time to return in 2013, the club could place him on injured reserve with the option to activate him later in the campaign. According to Darren Urban of AZCardinals.com, Arians indicated he hopes Cooper will be able to play this season.

Cooper was one of several key Cardinals who left Saturday’s game with injuries. Arians, per the club’s official Twitter feed, said that running back Rashard Mendenhall will have tests on his right knee. Also, nose tackle Dan Williams and tight end Rob Housler have ankle injuries, with Housler’s injury a high-ankle sprain, Arians said, according to the club.