McFadden sat out practice on Wednesday, Thursday and Friday with a hamstring injury. Tailback Rashad Jennings could see an increased workload with McFadden sidelined. The Raiders will also have fullback Marcel Reece available; he is active after being questionable with a knee injury.
The Raiders will be down three key offensive linemen, with center Stefen Wisniewski, right tackle Tony Pashos, and left tackle Menelik Watson all inactive. Strong safety Tyvon Branch, wide receiver Juron Criner and defensive tackle Stacy McGee are also out for Oakland.
The Chargers’ inactives are offensive tackle King Dunlap, nose tackle Kwame Geathers, wide receiver Lavelle Hawkins, offensive guard Chad Rinehart, quarterback Brad Sorensen, safety Brandon Taylor and outside linebacker Tourek Williams.