The Colts have officially lost starting left guard Donald Thomas for the season.
The team placed the 28-year-old Thomas on injured reserve Thursday, the club said.
Thomas suffered a torn quadriceps on Wednesday. He sustained the same injury last September.
With Thomas out, second-round pick Jack Mewhort is among the options to fill in at left guard.
In a corresponding roster move Thursday, the Colts re-signed undrafted rookie offensive lineman Eric Pike, who had a short stint with the club in May. A Towson product, Pike (6-5, 298) was a left tackle on the college level.
The signing of Pike puts the Colts back at the 90-player limit.