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Sickle cell trait causing leg pain for John Brown

Los Angeles Rams v Arizona Cardinals

GLENDALE, AZ - OCTOBER 02: Wide receiver John Brown #12 of the Arizona Cardinals during the NFL game against the Los Angeles Rams at the University of Phoenix Stadium on October 2, 2016 in Glendale, Arizona. (Photo by Christian Petersen/Getty Images)

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It looks like the Cardinals will have quarterback Carson Palmer in the lineup against the Seahawks on Sunday night after he practiced for a second straight day on Friday despite a hamstring injury that sidelined him on Wednesday.

It’s not looking so good for wide receiver John Brown. Brown missed a third straight day of practice with what the team had been calling a hamstring injury, although coach Bruce Arians said Friday that’s not quite accurate.

Per Arians, a blood test determined that Brown has a sickle cell trait that is causing Brown to experience pain in his leg. Work is being done to figure out a solution and the Cardinals haven’t ruled Brown out of the game, but it looks like there’s a decent chance he’ll be out of the lineup for the NFC West matchup.

Jaron Brown and J.J. Nelson could be in line for bigger roles if Brown can’t play as a result of the leg issue.