Coach Bruce Arians said Friday that Iupati is headed to injured reserve as a result of a bone spur in his elbow that will require him to have surgery. That will leave the Cardinals scrambling to fill out their offensive line in the near term because Alex Boone, who was starting in place of Iupati, will not play this week due to a pectoral injury.
As if that wasn’t enough, the team may also be without left tackle D.J. Humphries once again because of a knee injury. Arians said “we’ll see” when asked if Humphries could go against the 49ers this weekend.