The Bills are going to be without a pair of starters this weekend against the Bengals, with some injuries suffered last week.
Humber broke his hand last week against the Falcons, and Matthews will be out for a month after surgery to repair a broken thumb.
The Bills are also going to list cornerback E.J. Gaines as questionable for the game. He’s not going to practice today, and has been limited this week with a groin injury.