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Ryan Mathews injures shoulder, won’t return

San Diego Chargers v Pittsburgh Steelers

PITTSBURGH, PA - DECEMBER 9: Philip Rivers #17 of the San Diego Chargers hands off to Ryan Mathews #24 against the Pittsburgh Steelers during the game on December 9, 2012 at Heinz Field in Pittsburgh, Pennsylvania. (Photo by Justin K. Aller/Getty Images)

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The Chargers have many problems, but a familiar one just raised its head.

Running back Ryan Mathews has left the game with a left shoulder injury, and is doubtful to return. Mathews has struggled with durability and ball security, but today’s injury was to the opposite side as his broken collarbone earlier this season.

The Chargers are down 21-0 to the Panthers just before halftime, and with Ronnie Brown inactive, the Chargers are going to have to run with Jackie Battle, such that they’ll run.

UPDATE 5:26 P.M. ET: The Chargers announced that Mathews won’t return.