Vernon Davis leaves with hamstring injury

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The 49ers were without one of their most important offensive players for much of the fourth quarter of Sunday’s lopsided loss to Seattle.

Tight end Vernon Davis departed early in the period after suffering a hamstring injury. He was the intended target on Colin Kaepernick’s second interception of the game early in the fourth quarter. On the 49ers’ next drive, NBC’s Michelle Tafoya reported that Davis had ice on his leg and had been ruled out.

Davis caught three passes for 20 yards before leaving Sunday’s game. He hauled in six passes for 98 yards and two touchdowns in San Francisco’s Week One win against Green Bay.

Vance McDonald, Garrett Celek and Demarcus Dobbs are the 49ers’ other tight ends.