The Titans held on for a 20-17 victory.
It was Mike Vrabel‘s first win as head coach, coming against the team where he served as defensive coordinator last season.
Ryan Succop hit the game-winning field goal — a 31-yarder — with 1:00 remaining.
The Titans celebrated a game they weren’t expected to win without their starting quarterback, their starting tackles and their backup right tackle, among others. They won anyway, with Vrabel pulling out all the stops.
Jadeveon Clowney, who was inactive with elbow and back injuries, was flagged for taunting from the sideline. The 15-yard penalty aided the Titans in their game-tying drive to set up Succop’s 42-yard field goal with 9:43 left.
With the game tied 17-17, the Texans drove to the Titans 37. They punted, and Tennessee drove for the winning points.
Watson went 22-of-32 for 310 yards with two touchdowns and an interception. Hopkins caught six passes for 110 yards and a touchdown, while Will Fuller had eight catches for 113 yards and a touchdown.