Tight end George Kittle had catches of 18 and 22 yards and running back Matt Breida did the rest on the 49ers’ first touchdown drive of the night.
Breida’s 3-yard touchdown run has the 49ers back on top of the Giants, 10-7, with 13:05 remaining in the second quarter. The 49ers used eight plays to go 75 yards.
Breida has seven carries for 25 yards and a touchdown and also has drawn a 15-yard facemask penalty on Giants linebacker Nate Stupar.
Mullens has completed 6 of 7 passes for 60 yards and an interception.