Baker Mayfield has thrown three interceptions, including a pick-six, as the Texans have dominated the Browns on both sides of the ball.
Houston leads 23-0 at halftime.
Mayfield had not thrown three interceptions in the first half of a game since September 2013 when he played for Texas Tech in a game against TCU. Mayfield transferred to Oklahoma after the season.
The Texans have befuddled Mayfield, who is only 5-of-12 for 46 yards.
The Browns have only 74 yards.
The Texans have scored on all but one possession, gaining 262 yards.
Lamar Miller has rushed for 46 yards on 12 carries.
The Browns do have three sacks of Watson, including two by Myles Garrett.