Vernon is inactive with an abdominal injury. Adrian Clayborn will start in his place.
Cornerback Kevin Johnson (liver), cornerback Greedy Williams (shoulder), linebacker Mack Wilson (knee) and linebacker Jacob Phillips (knee) were ruled out Wednesday. Rookie receiver Donovan Peoples-Jones is the other inactive player for the Browns.
Receiver Auden Tate was a surprise healthy scratch after playing 15 snaps in Week One for the Bengals.
Cincinnati already had ruled out defensive tackles Geno Atkins (shoulder) and Mike Daniels (groin) and safety Shawn Williams (calf). The Bengals’ other inactives are running back Trayveon Williams and linebacker Markus Bailey.