The teams have combined for 48 points and 645 yards.
The Raiders and Chiefs are tied 24-24 at halftime after Las Vegas fell behind 21-10.
Ruggs has two catches for 118 yards and the touchdown, and Agholor has two catches for 67 yards and a score.
Mahomes is 14-for-27 for 237 yards and a touchdown. His touchdown pass was 8 yards to Sammy Watkins, who later limped off with a hamstring injury. Watkins is questionable to return.
Mahomes has a 3-yard touchdown run, and Hill ran for a 10-yard score. Travis Kelce has six catches for 95 yards, including a 23-yarder where Mahomes escaped the rush, rolled to his left and made a Houdini pass back to a sliding Kelce.
Hill has three catches for 78 yards, including a 37-yard, over-the-shoulder catch. The Raiders challenged, and replay showed Hill had both feet in bounds after making the catch.