So much for the COVID-19 outbreak and layoff affecting the Titans.
Tennessee, playing for the first time since Sept. 27 and after little practice, dominated the Bills from start to finish, winning 42-16. The Titans remained undefeated at 4-0, while the Bills suffered their first loss after four wins to open the season.
The Bills were their own worst enemy with three turnovers and 10 penalties. Josh Allen threw an interception on his first attempt, with Malcolm Butler getting the first of his two picks on the night. Butler had 97 yards in returns.
The Titans scored 21 points off the Bills’ turnovers, with scoring drives of 16, 12 and 18 yards.
Allen finished 26-of-41 for 263 yards with two touchdowns and two interceptions.
Tannehill’s touchdown run was 10 yards.
Brown, in his return from a knee injury in the season opener, made seven catches for 82 yards and the touchdown.