The Colts opened up a roster spot on Monday.
The team announced the release of running back Paul Perkins. Perkins signed to the practice squad last November and re-signed with the team in January.
Perkins was a 2016 fifth-round choice by the Giants and played 25 games for them over his first two seasons. He missed the 2018 season with a pectoral injury and played four games for the Lions in 2019.
Perkins has 165 carries for 575 yards and 24 catches for 217 yards over his entire career.