The 49ers have dealt with injuries to running backs all season and that will remain the case in Week Four against the Seahawks.
Elijah Mitchell is inactive for the game because of a shoulder injury. Mitchell was listed as questionable on Friday.
The 49ers have also scratched cornerback Josh Norman. Norman went to the hospital after a chest injury in last Sunday’s loss to the Packers and was listed as doubtful on Friday.
As expected, wide receiver Tyler Lockett is active for the Seahawks. Wide receiver Dee Eskridge, defensive end Benson Mayowa, cornerback John Reid, offensive lineman Brandon Shell, tackle Jamarco Jones, and defensive lineman L.J. Collier are inactive.