San Francisco 49ers schedule and results 2022: Dates, times, TV, opponents for Weeks 1-18 

NFL: DEC 12 49ers at Bengals
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The 49ers played the role of playoff spoiler last season, making it to the Conference Championship as a six seed before losing to the Rams, who would go on to win Super Bowl LVI. The team’s quarterback picture remains unclear heading into 2022, with Jimmy Garoppolo and Trey Lance both seemingly in contention for the starting job. Now that the full 18-week 2022 NFL schedule has been released, keep reading to see the 49ers’ full schedule, including dates, times, opponents, primetime games and more. Coverage of the latest news from around the NFL is available all year round on PFT’s Peacock channel. 

RELATED2022 Sunday Night Football schedule | Thanksgiving NFL schedule 2022 | Week 1 2022 NFL schedule 

49ers schedule 2022 (all times Eastern) 

  • Week 1: 9/11 Bears 19, 49ers 10 [recap]
  • Week 2: 9/18 49ers 27, Seahawks 7 [recap]
  • Week 3: 9/25 Broncos 11, 49ers 10 [recap]
  • Week 4: 10/3 49ers 24, Rams 9 [recap]
  • Week 5: 10/9 49ers 37, Panthers 15 [recap]
  • Week 6: 10/16 Falcons 28, 49ers 14 [recap]
  • Week 7: 10/23 Chiefs 44, 49ers 23 [recap]
  • Week 8: 10/30 49ers 31, Rams 14 [recap]
  • Week 9: BYE
  • Week 10: 11/13 49ers 22, Chargers 16 [recap]
  • Week 11: 11/21 49ers 38, Cardinals 10 [recap]
  • Week 12: 11/27 49ers 13, Saints 0 [recap]
  • Week 13: 12/4 49ers 33, Dolphins 17 [recap]
  • Week 14: 12/ 11 vs. Buccaneers, 4:25 PM, Fox
  • Week 15: 12/15 at Seahawks (Thursday), 8:15 PM, Amazon Prime Video
  • Week 16: 12/24 vs. Commanders (Saturday), 4:05 PM, CBS
  • Week 17: 1/1 at Raiders, 4:05 PM, Fox
  • Week 18: 1/7 or 1/8 vs. Cardinals, TBD, TBD

Prime-time games 

  • Sunday Night Football: Week 3 at Broncos, Week 10 vs. Chargers
  • Monday Night Football: Week 4 vs. Rams, Week 11 vs. Cardinals (Mexico City)
  • Thursday Night Football: Week 15 at Seahawks

RELATED: 2022 NFL schedule: All 32 teams’ home openers

Check out every teams’ 2022 NFL schedule below:

NFC: East (DAL | NYG | PHI | WAS), North (CHI | DET | GB | MIN), South (ATL | CAR | NO | TB), West (ARILARSF | SEA)

AFC: East (BUF | MIA | NE | NYJ), North (BAL | CIN | CLE | PIT), South (HOU | IND | JAX | IND), West (DEN | KC | LV | LAC)

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