Murray has not played since Week 9 against the Seahawks when he tweaked his hamstring.
The Cardinals will have receiver DeAndre Hopkins, who was questionable to play with a hamstring injury. He sat out one practice last week and had limited participation in two other workouts.
The Cardinals’ other inactives are cornerback Byron Murphy (back), linebacker Jesse Luketa, linebacker Victor Dimukeje, offensive tackle D.J. Humphries (back), offensive guard Max Garcia (shoulder) and tight end Zach Ertz (knee).
Garcia was questionable.
The 49ers won’t have defensive end Samson Ebukam (quadriceps/Achilles). He was questionable after being a limited practice participant on Friday and Saturday.
Ebukam missed last week’s game with his quadriceps injury and had the Achilles injury added to this week’s report.
Defensive lineman Arik Armstead (foot, ankle), running back Tyrion Davis-Price, linebacker Curtis Robinson, defensive lineman Kemoko Turay and offensive lineman Nick Zakelj are the 49ers’ other inactives.