The Eagles took the opening kickoff, and, after two incompletions, faced a third-and-10. Hurts scrambled for 24 yards before Rudy Ford pushed him out of bounds.
Later in the drive, on third-and-six from the Green Bay 34, Hurts ran for 28.
Gainwell was in the end zone two plays later, giving the Eagles a 7-0 lead with 11:19 remaining in the first quarter.
Sanders had three carries for 11 yards and Gainwell two for 6.
Hurts completed 1 of 3 passes for 6 yards.
Packers safety Darnell Savage was injured on Hurts’ first carry and is questionable to return with a foot injury.